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This report—the second of a series on codeine and its alternates for pain and cough relief—contains a detailed evaluation of experimental and clinical data on newer substances having analgesic properties comparable to and in approximately the same range as those of codeine. The data are discussed under the headings: analgesic effects in animals; clinical usefulness; side-effects with particular reference to dependence and abuse liability.
Pain is Mackay bay personals common in patients with cancer. Opioid analgesics, including codeine, play a ificant role in major guidelines on the management of cancer pain, particularly for mild to moderate pain.
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